Annual report [Section 13 and 15(d), not S-K Item 405]

Asset Purchase and Merger Agreements (Narrative) (Details)

v3.26.1
Asset Purchase and Merger Agreements (Narrative) (Details)
1 Months Ended 12 Months Ended
Nov. 05, 2025
USD ($)
Jul. 28, 2025
USD ($)
May 13, 2025
Jul. 15, 2024
USD ($)
Feb. 24, 2021
USD ($)
Sep. 30, 2025
USD ($)
Jun. 30, 2024
USD ($)
Dec. 31, 2023
D
Dec. 31, 2025
USD ($)
Dec. 31, 2024
USD ($)
Nov. 30, 2025
USD ($)
Jul. 31, 2022
USD ($)
Business Combination [Line Items]                        
Gain from deconsolidation of subsidiary                 $ 27,127,000 $ 0    
Number of days to dispose of assets purchased     180 days                  
Collaboration revenue                   1,500,000    
Other                 3,146,000 4,915,000    
Assets held for sale                 $ 0 1,165,000    
Baergic                        
Business Combination [Line Items]                        
Gain from deconsolidation of subsidiary $ 200,000                      
Disposal group, not discontinued operations | Baergic                        
Business Combination [Line Items]                        
Upfront payment receivable                     $ 300,000  
Percentage of expected receivables to all future payments and royalties payable                     74.00%  
Crystalys Therapeutics, Inc                        
Business Combination [Line Items]                        
Capitalization in equity securities       $ 150,000,000                
Crystalys Therapeutics, Inc | UBriGene                        
Business Combination [Line Items]                        
Percentage of royalty on future net sales       3.00%                
Urica's equity position                 15.00%      
Assets Sold under Agreements to Repurchase, Accretion Expense                   700,000    
Maximum | Disposal group, not discontinued operations | Baergic                        
Business Combination [Line Items]                        
Milestone payments receivable                     $ 79,000,000  
Mustang                        
Business Combination [Line Items]                        
Other                 $ 1,300,000 1,300,000    
Mustang | UBriGene                        
Business Combination [Line Items]                        
Consideration transferred   $ 6,000,000         $ 4,700,000          
Repurchased assets on relative fair value basis             2,200,000          
Purchase price             1,400,000          
Gain on sale of asset   1,400,000                    
Expenses related to transactions having to do with sale of assets.   $ 300,000                    
Upfront payment             100,000          
Subsequent amount             $ 1,300,000          
Subsequent payment due period             12 months          
Asset acquisition consideration, threshold net assets considered for delay in subsequent payment             $ 20,000,000          
Interest rate on outstanding liability             5.00%          
Fair value of supplies received by partner company expensed to research and development             $ 2,500,000          
Subsequent payment extended due period             6 months          
Cyprium | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Consideration received         $ 8,000,000              
Number of days to assume control over development of CUTX-101 in the event that CUTX-101 NDA approval has not been obtained         45     45        
Collaboration revenue                 1,500,000 4,500,000    
Development and regulatory milestone payments receivable         $ 128,000,000              
Urica                        
Business Combination [Line Items]                        
Percentage of equity to be held       35.00%                
Repurchase option liability           $ 2,600,000            
Urica | Asset Purchase, Royalty And Related Agreements With Crystalis                        
Business Combination [Line Items]                        
Consideration transferred       $ 6,400,000                
Reimbursement for clinical costs       600,000                
Amount of minimum qualified financing required       $ 120,000,000                
Urica | Crystalys Therapeutics, Inc                        
Business Combination [Line Items]                        
Royalty Income                 0 0    
Urica's equity position       15.00%                
Assets Sold under Agreements to Repurchase, Accretion Expense                 1,300,000      
Avenue | Avenue Share Repurchase Agreement                        
Business Combination [Line Items]                        
Total payments made                 1,400,000      
Avenue | InvaGen | Avenue Share Repurchase Agreement                        
Business Combination [Line Items]                        
Percentage of contingent fee payable                       7.50%
Contingent fee payable from proceeds of future financing                       $ 4,000,000
Contingent fees paid                   $ 700,000    
Payments of milestones                 $ 200,000      
Annual net sales up to $75 million | Cyprium | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Percentage of royalty on future net sales         3.00%              
Annual net sales up to $75 million | Cyprium | Maximum | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Annual net sales as basis for milestone payments         $ 75,000,000              
Annual net sales between $75 million and $100 million | Cyprium | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Percentage of royalty on future net sales         8.75%              
Annual net sales between $75 million and $100 million | Cyprium | Minimum | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Annual net sales as basis for milestone payments         $ 75,000,000              
Annual net sales between $75 million and $100 million | Cyprium | Maximum | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Annual net sales as basis for milestone payments         $ 100,000,000              
Annual net sales in excess of $100 million | Cyprium | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Percentage of royalty on future net sales         12.50%              
Annual net sales in excess of $100 million | Cyprium | Minimum | Development and Asset Purchase Agreement w/Sentynl                        
Business Combination [Line Items]                        
Annual net sales as basis for milestone payments         $ 100,000,000              
Upon occurrence of development and regulatory events | Disposal group, not discontinued operations | Baergic                        
Business Combination [Line Items]                        
Milestone payments receivable                     2,500,000  
Each indication after occurrence of development and regulatory events | Disposal group, not discontinued operations | Baergic                        
Business Combination [Line Items]                        
Milestone payments receivable                     $ 1,500,000