Annual report pursuant to Section 13 and 15(d)

Accounts Payable and Accrued Expenses (Details)

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Accounts Payable and Accrued Expenses (Details) - USD ($)
$ in Thousands
Dec. 31, 2021
Dec. 31, 2020
Accrued expenses:    
Accounts Payable $ 47,429 $ 11,412
Professional fees 1,835 1,236
Salaries, bonus and related benefits 8,809 6,701
Research and development 7,932 5,007
Research and development - manufacturing 0 518
Research and development - license maintenance fees 4,640 461
Research and development - milestones 850 600
Accrued royalties payable 3,833 2,682
Accrued coupon expense 10,603 12,869
Income taxes payable 0 136
Return reserve 3,240 2,580
Other 1,489 1,187
Total accounts payable and accrued expenses $ 90,660 $ 45,389