Stockholders' Equity - Additional Information (Detail)

v3.8.0.1

Stockholders' Equity - Additional Information (Detail) - USD ($)			1 Months Ended																	3 Months Ended		9 Months Ended		12 Months Ended
	Jul. 15, 2015	Jun. 01, 2015	Dec. 01, 2017	Nov. 30, 2017	Nov. 30, 2017	Oct. 31, 2017	Jun. 26, 2017	Jun. 01, 2017	Jan. 31, 2017	Dec. 31, 2016	Jun. 01, 2016	May 31, 2016	Feb. 23, 2016	Jan. 31, 2016	Jan. 02, 2016	Dec. 02, 2015	Oct. 30, 2015	Sep. 18, 2015	Jun. 30, 2013	Dec. 31, 2016	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Dec. 15, 2017	Oct. 26, 2017	Jun. 02, 2015	Mar. 17, 2014
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Based compensation, authorized number of shares																								12,506,679
Employee Stock Purchase Plan to eligible employees, Reckoning fair value percentage during offering period			85.00%					85.00%																85.00%
Employee Stock Purchase Plan to eligible employees, compensation expense recognized																								$ 200,000	$ 0.1	$ 45,000
Common Stock issued in connection with the first ESPP offering			45,657					22,076
Share Based Compensation Restricted Stock Units																								$ 11,300,000	$ 9,900,000	6,900,000
Common Stock Par Or Stated Value Per Share			$ 3.26					$ 1.90		$ 0.001										$ 0.001				$ 0.001	$ 0.001
Share Price			$ 3.83					$ 2.24
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized																								12,506,679
Proceeds from Stock Options Exercised																								$ 27,000	$ 0	216,000
Class of Warrant or Right, Exercise Price of Warrants or Rights							$ 4.02											$ 7.00						$ 2,500
Stock Issued During Period, Shares, Issued for Services													10,000
Class of Warrant or Right, Number of Securities Called by Warrants or Rights																								7.00
Proceeds from issuance of Common stock							$ 34,200,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Additional Shares Authorized																								7,700,000
Share-based Compensation																								$ 14,005,000	12,128,000	14,291,000
Net Proceeds From Issuance Of Warrants																								$ 51,500,000
Stock Issued For Exercise Of Warrants																								10,000
Warrant Purchase Price Per Unit																								$ 50,000
Common Stock, Capital Shares Reserved for Future Issuance																								125,000
Stock Issued During Period Shares warrants Exercised																		2,500
Stock Issued During Period, Shares, New Issues						43,292												10,000
Stock Issued During Period, Value of Warrants Excercised																		$ 50,000
Equity Method Investment, Ownership Percentage																														35.00%
Warrants Issued																	139,592
Stock Issued During Period, Value, New Issues																									53,000,000
Payments of Stock Issuance Costs																								$ 2,804,000	0	0
Adjustments To Additional Paid In Capital At Market Offering Costs																									$ (79,000)
Preferred Stock Shares Outstanding										0										0				1,000,000	0
Preferred Stock Shares Authorized										15,000,000										15,000,000				15,000,000	15,000,000
Preferred Stock, Value, Issued										$ 0										$ 0				$ 1,000	$ 0
Preferred Stock Shares Issued										0										0				1,000,000	0
Dividends, Preferred Stock																								$ 299,000
Proceeds from Issuance of Preferred Stock and Preference Stock																								$ 25,000,000	$ 0	$ 0
Payments for Other Fees				$ 2,700,000	$ 100,000																	$ 1,265,000
Proceeds from Fees Received																						14,420,000	$ 1,265,000
Percentage of Placement of Agent Fee																		10.00%						10.00%
Common Stock Shares Outstanding										48,932,023										48,932,023				50,991,285	48,932,023
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized																								$ 0
Employee Service Share Based Compensation Vested Awards Total Compensation Cost Not Yet Recognized																								0
Common Stock Value							800,000			$ 49,000										$ 49,000				$ 51,000	$ 49,000
Payments for Fees				$ 2,700,000	$ 100,000																	$ 1,265,000
Market Offering [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares Issued, Price Per Share												$ 2.89
Proceeds from issuance of Common stock												$ 400,000
Issuance of Common Stock for At the Market Offering in shares												150,556
Adjustments To Additional Paid In Capital At Market Offering Costs												$ 79,000
IPO [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Fees and Commissions							$ 2,300,000
Plan 2013 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Based compensation, authorized number of shares																								10,000,000
Stock Based compensation, shares available for issuance																								3,493,321
Employee Stock Purchase Plan to eligible employees, compensation expense recognized																								$ 2,300,000,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized																								10,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant																								3,493,321
Plan 2007 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Based compensation, authorized number of shares										1,500,000										1,500,000				6,000,000	1,500,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized										1,500,000										1,500,000				6,000,000	1,500,000
Longterm Incentive Program [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested in Period, Fair Value																								$ 1,500,000	$ 1,400,000
Class of Warrant or Right, Outstanding	500,000
Weighted Market Value Percentage of Invested Capital	44.80%
Weighted Average Cost Percentage of Capital	30.00%
Stock Issued During Period, Shares, Issued for Services																								500,000
Capital Units, Authorized																								100,000,000
Share-based Compensation																								$ 600,000	300,000
Sharebased Compensation Arrangement By Sharebased Payment Award Percentage Of Shares Granted															1.00%
Noncontrolling Interest, Ownership Percentage by Noncontrolling Owners																								5.00%
Plan 2017 and 2013 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Based compensation, shares available for issuance																										16,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant																										16,000,000
Series A Preferred Stock [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares Issued, Price Per Share				$ 25.0	$ 25.0
Stock Issued During Period, Value, New Issues				$ 25,000,000
Adjustments To Additional Paid In Capital At Market Offering Costs																									$ 0
Preferred Stock Shares Outstanding										0										0					0
Preferred Stock Shares Authorized																												5,000,000
Preferred Stock, Value, Issued																											$ 25,000,000
Preferred Stock Shares Issued										0										0					0		1,000,000
Preferred Stock, Dividend Rate, Percentage				9.375%																				9.375%
Dividends Payable, Amount Per Share																								$ 0.299479			$ 2.34375
Dividends, Preferred Stock																								$ 0
Preferred Stock, Liquidation Preference Per Share																								$ 25.00
Proceeds from Issuance of Preferred Stock and Preference Stock				$ 22,200,000
After Amendment [Member] | Convertible Preferred Stock [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Price																								$ 0.001
Capital Units, Authorized																								100,000,000
Checkpoint [Member] | Private Placement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights													$ 7.00
Stock Issued During Period, Value, Restricted Stock Award, Net of Forfeitures, Total													$ 126,640
Class of Warrant or Right, Number of Securities Called by Warrants or Rights													3,500
Warrant Purchase Price Per Unit													$ 45,000
Proceeds from Issuance of Private Placement													$ 600,000
Warrants Issued													44,324
Chief Executive Officer [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross																								1,900,000
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost																								$ 2,500,000	$ 400,000
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting year																								December 2022
Former Board Of Director [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Restricted Stock Units	$ 133,000
Dr. Rosenwald [Member] | Longterm Incentive Program [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period									552,698					510,434
Mustang [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Based compensation, authorized number of shares																								8,610,774
Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Authorized																								8,610,774
Stock Issued During Period, Value, New Issues																								$ 56,000,000
Warrants Issued number																								2,152,693
Proceeds from Fees Received																								$ 5,600,000
Percentage of Placement of Agent Fee																								10.00%
Warrants Issued on During Period																								861,077
Senior Vice President [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage	50.00%
Stock Issued During Period, Value, Issued for Services																								$ 300,000	$ 1,200,000	$ 1,900,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross																			200,000
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost	$ 3,700,000
Non-employee [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation																										3,000,000
Avenue Therapeutics, Inc. [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Shares Issued, Price Per Share							$ 6.00
Mustang Bio, Inc [Member] | Private Placement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights																					$ 8.50		$ 8.50
Stock Issued During Period, Value, New Issues																					$ 39,100,000
Mustang Bio, Inc [Member] | Market Offering [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Issued During Period Shares warrants Exercised																				2,500
Stock Issued During Period, Value of Warrants Excercised																				$ 65,000
Checkpoint Therapeutics, Inc [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Equity Method Investment, Ownership Percentage																								37.70%
Stock Issued During Period, Value, New Issues																								$ 57,800,000
National Holdings Corporation [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Class of Warrant or Right, Exercise Price of Warrants or Rights																					$ 3.25		$ 3.25
Class of Warrant or Right, Number of Securities Called by Warrants or Rights							125,000
National Holdings Corporation [Member] | Private Placement [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock Issued During Period Shares warrants Exercised																				10
Payments of Stock Issuance Costs																				$ 3,900,000
Private Placement Stock Units Shares To Be Issued										10,000										10,000					10,000
Warrants Issued During Period																								601,486
National Securities Corp [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Payments for Other Fees				2,100,000
Payments for Fees				$ 2,100,000
Research and Development Expense [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Allocated Share-based Compensation Expense																								$ 4,000,000	$ 4,700,000	5,800,000
General and Administrative Expense [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Allocated Share-based Compensation Expense																								10,000,000	7,400,000	8,500,000
General and Administrative Expense [Member] | Longterm Incentive Program [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation																								$ 100,000	$ 18,000	2,200,000
Restricted Stock [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share Based Compensation Restricted Stock Units																										$ 400,000
Deferred Compensation Arrangement with Individual, Shares Issued																								230,000	230,000	290,000
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Granted in Period, Fair Value																								$ 3,600,000	$ 3,400,000
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period																								1,325,396	1,240,868
Restricted Stock Units (RSUs) [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition																								4 years 7 months 6 days
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options																								$ 3,200,000
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Granted in Period, Fair Value																								$ 4,700,000	$ 1,800,000
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period																								1,128,750	641,000
Restricted Stock Units (RSUs) [Member] | Senior Vice President [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross	1,000,000
Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested, Number of Shares																								150,000	150,000	300,000
New Award [Member] | Senior Vice President [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost	$ 3,300,000
Old Award [Member] | Senior Vice President [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Plan Modification, Incremental Compensation Cost	$ 400,000
Employee Stock Option [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Employee Stock Purchase Plan to eligible employees, Reckoning fair value percentage during offering period										85.00%						85.00%				85.00%					85.00%				85.00%
Employee Stock Purchase Plan to eligible employees, Number of shares purchased by employees	85
Common Stock issued in connection with the first ESPP offering		14,681								52,769	33,958					13,317								245,652
Common Stock Par Or Stated Value Per Share	$ 2.40															$ 2.41													$ 1.80
Share Price										$ 2.39	$ 2.82					$ 2.84				$ 2.39					$ 2.39				$ 2.12
Proceeds from Stock Options Exercised																								$ 27,000	$ 0	$ 200,000
Common Stock, Capital Shares Reserved for Future Issuance																								154,348
Unvested Restricted Stock Units [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Employee Service Share-based Compensation, Nonvested Awards, Compensation Cost Not yet Recognized, Period for Recognition																								1 year 6 months
Employee Service Share-based Compensation, Nonvested Awards, Compensation Not yet Recognized, Stock Options																								$ 3,400,000