Debt and Interest- Additional Information (Detail)

v3.8.0.1

Debt and Interest- Additional Information (Detail) - USD ($)					1 Months Ended															9 Months Ended		12 Months Ended
	Jan. 02, 2018	Jul. 05, 2017	Sep. 14, 2016	Feb. 13, 2014	Feb. 28, 2018	Nov. 30, 2017	Nov. 30, 2017	Sep. 30, 2017	Aug. 31, 2017	Jul. 31, 2017	Jun. 30, 2017	May 31, 2017	May 02, 2017	Mar. 31, 2017	Oct. 25, 2016	Sep. 30, 2016	Jun. 30, 2016	Feb. 29, 2016	Oct. 30, 2015	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015	Mar. 16, 2018	Jun. 26, 2017	Jul. 31, 2016	Oct. 31, 2015	Sep. 18, 2015	Mar. 31, 2015
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights																						7.00
Warrant exercise price																						$ 2,500				$ 4.02			$ 7.00
Debt Instrument, Interest Rate, Stated Percentage																						28.00%
Debt discount recorded																						$ 1,035,000	$ 2,009,000
Cash proceeds from 2008 Senior Convertible Notes																						0	920,000	$ 0
Notes Payable																						$ 66,509,000	28,215,000
Debt Instrument, Maturity Date, Description																						May - 2018
Debt Instrument, Unamortized Discount (Premium), Net, Total																							400,000
Percentage of Cash Flow Pursuant to ASC 470																						10.00%
Fair Value Adjustment of Warrants																						$ (8,391,000)	1,039,000	438,000
Legal Fees								$ 1,500,000								$ 200,000
Payments for Other Fees						$ 100,000	$ 2,700,000													$ 1,265,000
Convertible Notes Payable, Current																						4,700,000	1,031,000
Proceeds from Fees Received																				$ 14,420,000	$ 1,265,000
Proceeds from Convertible Debt																						9,914,000	4,609,000	0
Payments of Financing Costs																						$ 0	0	855,000
Subsequent Event [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage					8.00%
Debt Instrument, Face Amount					$ 6,500,000
Debt Instrument, Maturity Date, Description					Each Note matures on the 24 month anniversary of issuance, provided that the Company may extend the maturity date for two six-month periods.
Maturity Date					Mar. 31, 2018
Letter of Credit [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage																						2.00%
Letters of Credit Outstanding, Amount																						$ 2,000,000
Minimum [Member]
Debt [Line Items]
Warrant exercise price																						$ 3.61
Maximum [Member]
Debt [Line Items]
Warrant exercise price																						$ 4.75
Israel Discount Bank Of New York [Member]
Debt [Line Items]
Current portion of note payable																						$ 14,900,000	14,900,000
Debt Instrument, Fee Amount				$ 15,000,000
Notes Payable																							$ 14,900,000
IDB Promissory Note Payable [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage																							2.25%
Debt Instrument, Unused Borrowing Capacity, Amount				100,000
Debt Instrument, Periodic Payment				14,000,000
Debt Instrument, Fee Amount				$ 15,000,000
Opus Credit Facility [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage			12.00%
Class Of Warrant Or Right Value Of Securities Called By Warrants Or Rights			$ 1,500,000
Class Of Warrant Or Right Exercise Price Percentage Of Warrants Or Rights			3.00%
Legal Fees			$ 25,000,000
Warrants and Rights Outstanding																						$ 9,500,000	$ 7,000,000
Maturity Date			Sep. 14, 2018
Opus Credit Facility [Member] | Subsequent Event [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage																									12.00%
NSC Notes Payable [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage																						8.00%	8.00%
Debt discount recorded																											$ 600,000
Debt Instrument, Face Amount																								900,000
Long-term Debt, Gross																											$ 3,600,000
Notes Payable																														$ 10,000,000
Debt Instrument, Term																						10 years
Debt Instrument, Maturity Date, Description																						Sep - 2018
Debt Instrument, Interest Rate, Effective Percentage																						14.00%	17.83%
Contingently Issuable Warrants Percentage																						25.00%					25.00%
Helocyte Convertible Note One [Member]
Debt [Line Items]
Debt Instrument, Term																	18 months
Debt Instrument, Maturity Date, Description																						December 2017
Proceeds from Issuance or Sale of Equity																	$ 10,000,000
Class Of Warrant Or Right Value Of Securities Called By Warrants Or Rights																							$ 400,000
Class Of Warrant Or Right Exercise Price Percentage Of Warrants Or Rights																							110.00%
Legal Fees																							$ 100,000
Helocyte Convertible Note One [Member] | Subsequent Event [Member]
Debt [Line Items]
Repayments of Long-term Debt	$ 1,000,000
Helocyte Convertible Note One [Member] | Conversion One [Member]
Debt [Line Items]
Debt Instrument, Convertible, Terms of Conversion Feature																	(a) the lowest price per share at which equity securities of Helocyte are sold in such sale less a 33% discount and (b) a per share price based on a pre-offering valuation of $50.0 million divided by the number of common shares outstanding on a fully-diluted basis.
Helocyte Convertible Note One [Member] | Conversion Two [Member]
Debt [Line Items]
Debt Instrument, Convertible, Terms of Conversion Feature																	(a) a discount to the price per share being paid in the Sale of Helocyte equal to 33% or (b) a conversion price per share based on a pre-sale valuation of $50.0 million divided by the fully-diluted common stock of Helocyte immediately prior to the Sale of Helocyte (excluding the notes).
Helocyte Convertible Note One [Member] | Minimum [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage																							5.00%
Avenue Convertible Note [Member]
Debt [Line Items]
Subsequent private placement																							$ 200,000
Debt Instrument, Term																							18 months
Debt Instrument, Maturity Date, Description																						June - 2018
Debt Related Commitment Fees and Debt Issuance Costs																						$ 3,000	$ 70,000	0
Debt Instrument, Convertible, Terms of Conversion Feature																						(a) the lowest price per share at which equity securities of Helocyte are sold in such sale less a 33% discount and (b) a per share price based on a pre-offering valuation of $50.0 million divided by the number of common shares outstanding on a fully-diluted basis.
Proceeds from Issuance or Sale of Equity																							10,000,000
Class Of Warrant Or Right Value Of Securities Called By Warrants Or Rights																							10,000
Legal Fees																							$ 44,000
Debt Instrument, Interest Rate, Stated Percentage,Current Year																							5.00%
Net Proceeds From Issuance Of Private Placement After Paying Fees																							$ 100,000
Payments for Other Fees																							58,000
Paymens For Placement Fee																							10,000
Professional Fees																							4,000
Convertible Notes Payable, Current																						$ 0	$ 200,000
Placement Fee Percentage																						10.00%	10.00%
Avenue Convertible Note [Member] | Conversion One [Member]
Debt [Line Items]
Debt Instrument, Convertible, Terms of Conversion Feature																							(a) the lowest price per share at which equity securities of Avenue are sold in such sale less a 33% discount and (b) a per share price based on a pre-offering valuation of $30.0 million divided by the number of common shares outstanding on a fully-diluted basis.
Avenue Convertible Note [Member] | Conversion Two [Member]
Debt [Line Items]
Debt Instrument, Convertible, Terms of Conversion Feature																							(a) a discount to the price per share being paid in the Sale of Avenue equal to 33% or (b) a conversion price per share based on a pre-sale valuation of $30.0 million divided by the fully-diluted common stock of Avenue immediately prior to the Sale of Avenue (excluding the Avenue Notes).
Helocyte Convertible Note [Member] | Maximum [Member]
Debt [Line Items]
Debt Instrument, Face Amount																							$ 5,000,000
Caelum Convertible Note [Member]
Debt [Line Items]
Debt Instrument, Face Amount										$ 10,000,000
Debt Related Commitment Fees and Debt Issuance Costs																						$ 100,000	0	0
Class Of Warrant Or Right Exercise Price Percentage Of Warrants Or Rights																						110.00%
Class of Warrant or Right Exercise Price Description																						the exercise price will be $75 million dollars divided by the total number of fully-diluted shares of Common Stock outstanding immediately prior to exercise of the warrant, giving effect to the assumed conversion of all options, warrants, and convertible securities of the Company .
Debt Conversion, Description																						The notes convert upon a qualified financing in which Caelum raises gross proceeds of at least $10 million as follows: the lesser of (a) a discount to the price per common share being paid in the Sale of the Company equal to 20% or (b) a conversion price per share based on a pre-sale valuation of $75,000,000 divided by the number of common shares outstanding at that time assuming the hypothetical conversion or exercise of any convertible securities, options, warrants and other rights to acquire common shares of the Company.
Percentage Of Placement Agent Fee																						10.00%
Debt Instrument Issuance Percentage of Commission										10.00%
Proceeds from Convertible Debt																						$ 9,900,000
Payments of Financing Costs																						$ 900,000
Class of Warrant or Right Percentage Securities Called by Warrants or Rights																						10.00%
NSC 2017 Note [Member]
Debt [Line Items]
Debt Instrument, Interest Rate, Stated Percentage														8.00%
Debt Instrument, Face Amount														$ 3,250,000
Debt Instrument, Maturity Date, Description																						Each Note is due on the third anniversary of its issuance, provided that the Company may extend the maturity date for two one-year periods in its sole discretion.
Paid-in-kind Interest Percentage														7.00%
Line of Credit Facility, Current Borrowing Capacity														$ 50,000,000
Percentage Of Placement Agent Fee														10.00%
Warrant on Sale Price of Note Percentage														10.00%
NSC 2017 Note [Member] | First Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights														87,946
Warrant exercise price														$ 3.70
Cash proceeds from 2008 Senior Convertible Notes														$ 3,200,000
Proceeds from Fees Received														300,000
NSC 2017 Note [Member] | Secoud Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights													234,438
Warrant exercise price													$ 3.65
Cash proceeds from 2008 Senior Convertible Notes													$ 8,600,000
Proceeds from Fees Received													$ 900,000
NSC 2017 Note [Member] | Third Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights												147,806
Warrant exercise price												$ 3.61
Cash proceeds from 2008 Senior Convertible Notes												$ 5,300,000
Proceeds from Fees Received												$ 500,000
NSC 2017 Note [Member] | Fourth Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights											38,315
Warrant exercise price											$ 4.75
Cash proceeds from 2008 Senior Convertible Notes											$ 1,800,000
Proceeds from Fees Received											$ 200,000
NSC 2017 Note [Member] | Fifth Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights									63,526
Warrant exercise price									$ 4.75
Cash proceeds from 2008 Senior Convertible Notes									$ 3,000,000
Proceeds from Fees Received									$ 300,000
NSC 2017 Note [Member] | Sixth Closing [Member]
Debt [Line Items]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights								144,149												144,149
Warrant exercise price								$ 4.42												$ 4.42
Cash proceeds from 2008 Senior Convertible Notes								$ 6,400,000
Proceeds from Fees Received								$ 600,000
NSC 2017 Note [Member] | Maximum [Member]
Debt [Line Items]
Debt Instrument, Face Amount														$ 40,000,000
NSC [Member]
Debt [Line Items]
Repayments of Debt		$ 3,600,000
Checkpoint [Member]
Debt [Line Items]
Debt Instrument, Unamortized Discount (Premium), Net, Total																		$ 300,000
Long-term Debt, Fair Value																		200,000
Fees Related To Loan Issuance Costs																		$ 2,800,000
Checkpoint [Member] | NSC Notes Payable [Member]
Debt [Line Items]
Debt Related Commitment Fees and Debt Issuance Costs																								2,800,000
Avenue [Member] | NSC Notes Payable [Member]
Debt [Line Items]
Debt Related Commitment Fees and Debt Issuance Costs																								3,000,000
Warrant to NSC [Member]
Debt [Line Items]
Approximate fair value of the warrant																			$ 600,000
Debt discount recorded																												$ 200,000
Share-based Compensation Arrangement by Share-based Payment Award, Non-Option Equity Instruments, Granted																			139,592
Share-based Compensation, Shares Authorized under Stock Option Plans, Exercise Price Range, Exercisable Options, Weighted Average Exercise Price															$ 0.0001				$ 0.0001
Fair Value Adjustment of Warrants															$ 800,000				$ 400,000
Share Based Compensation Arrangement By Share Based Payment Award Non Option Equity Instruments Issued															138,462
Contingently Issuable Warrants issued in connection with NSC Note Avenue [Member]
Debt [Line Items]
Debt Instrument, Unamortized Discount (Premium), Net, Total																							$ 100,000					$ 100,000
Mustang [Member] | NSC Notes Payable [Member]
Debt [Line Items]
Debt Related Commitment Fees and Debt Issuance Costs																								$ 3,600,000