Annual report pursuant to Section 13 and 15(d)

Milestones and Sponsored Research Agreements - Additional Information (Detail)

v3.19.1
Milestones and Sponsored Research Agreements - Additional Information (Detail) - USD ($)
1 Months Ended 12 Months Ended
Mar. 12, 2018
Jan. 03, 2018
Jul. 03, 2017
Mar. 05, 2015
Oct. 29, 2018
Nov. 30, 2017
Nov. 28, 2017
Jun. 30, 2017
Feb. 17, 2017
Mar. 31, 2016
Feb. 29, 2016
Dec. 31, 2018
Dec. 31, 2017
Oct. 31, 2016
Research and Development Expense                       $ 83,333,000 $ 48,322,000  
Payment of Upfront Fees                       1,000,000    
Payments to Acquire in Process Research and Development                       1,074,000 3,365,000  
Reimbursement Of Cost Recognized As Revenue                       35,000 600,000  
Revenue Recognition Milestone Method Payments Due         $ 2,000,000                  
Sponsor Research Agreement Funding Commitment   $ 900,000       $ 2,300,000                
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross $ 100,000                          
Research and Development Arrangement, Contract to Perform for Others, Description and Terms   2 year                        
SPR Sponsored Research Agreement [Member]                            
Research and Development Expense                       100,000 100,000  
Revenue Recognition Milestone Method Payments Due Over Three Years             $ 800,000              
Checkpoint Therapeutics, Inc [Member]                            
Stock Issued During Period, Value, Purchase of Assets                       22,000,000    
AR CD123 License [Member]                            
Revenue Recognition Milestone Method Payments Due Over Three Years                 $ 200,000          
UPenn Sponsored Research Agreement [Member]                            
Research and Development Expense                       500,000    
Payments For Research And Development Expenses                       300,000    
Sponsor Research Agreement Funding Commitment                       2,000,000    
Umass Sponsored Research Agreement [Member]                            
Research and Development Expense                       800,000    
Payments For Research And Development Expenses                       800,000    
Sponsor Research Agreement Funding Commitment                       800,000    
Pep Vax [Member]                            
Payments For Research And Development Expenses                       100,000 1,100,000  
Triplex [Member]                            
Payments For Research And Development Expenses                         2,600,000  
Helocyte Inc [Member]                            
Payments For Research And Development Expenses                       100,000 3,700,000  
Payment of Upfront               $ 1,500,000            
Mustang Bio, Inc [Member]                            
Research And Development Expense Payable Milestone Payment                 200,000          
Research and Development Expense                       1,300,000 600,000  
Payment of Upfront Fees                 9,300          
Revenue Recognition Milestone Method Payments Due                 100,000          
Mustang Bio, Inc [Member] | AR IL-13 License [Member]                            
Research and Development Expense                       1,100,000 1,400,000  
Mustang Bio, Inc [Member] | CD20 Technology License [Member]                            
Payment of Upfront Fees     $ 5,300,000                      
UCLB [Member]                            
Payment of Upfront Fees                       $ 100,000    
UCLB [Member] | Minimum [Member]                            
Royalty Percentage                       3.00%    
UCLB [Member] | Maximum [Member]                            
Royalty Percentage                       5.00%    
Cellvation [Member]                            
Research And Development Expense Payable Milestone Payment                           $ 800,000
Research and Development Expense                       $ 300,000 100,000  
City Of Hope [Member]                            
Research And Development Expense Payable Milestone Payment                   $ 2,000,000 $ 3,400,000      
Research and Development Expense                       500,000 0  
Payments to Acquire in Process Research and Development                   $ 1,000,000 $ 1,000,000      
City Of Hope [Member] | AR CD123 License [Member]                            
Research and Development Expense                       800,000 1,400,000  
Payment of Upfront Fees                 20,000          
Revenue Recognition Milestone Method Payments Due                 $ 100,000          
Pentamer [Member]                            
Payments For Research And Development Expenses                       1,300,000 200,000  
Mustag [Member] | COH [Member]                            
Research and Development Expense                       2,000,000 2,000,000  
Amount payable for research       $ 2,000,000                    
Tamid [Member]                            
Research and Development Expense                       $ 700,000 $ 100,000  
Research and development payments due           $ 800,000