Quarterly report pursuant to Section 13 or 15(d)

Accrued Expenses and Other Long-Term Liabilities - Additional Information (Detail)

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Accrued Expenses and Other Long-Term Liabilities - Additional Information (Detail) (USD $)
3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Sep. 30, 2014
Sep. 30, 2013
Dec. 31, 2013
Sep. 30, 2014
Manufacturing Facility [Member]
Sep. 30, 2014
Manufacturing Facility [Member]
Sep. 30, 2014
Ovamed Manufacturing Rights [Member]
Dec. 31, 2012
Ovamed Manufacturing Rights [Member]
Sep. 30, 2014
Woburn MA facility [Member]
Sep. 30, 2014
New York NY Office Space [Member]
Sep. 30, 2014
New York NY Office Space [Member]
Sep. 30, 2014
Lease Agreements [Member]
Sep. 30, 2014
Lease Agreements [Member]
Sep. 30, 2014
Chief Medical Officer [Member]
Sep. 30, 2014
Chief Medical Officer [Member]
Schedule Accrued Expenses And Other Long-Term Liabilities [Line Items]                                
Other Research and Development Expense                         $ 0 $ 800,000    
Lease Expiration Date                   Feb. 28, 2018   May 31, 2016        
Severance Costs                               400,000
Payments for Postemployment Benefits                             300,000 1,700,000
Operating Leases, Rent Expense     700,000               35,000 82,000        
Impairment of Long-Lived Assets Held-for-use     300,000                          
Other Liabilities                 1,500,000              
Other Accrued Liabilities Current 208,000   208,000   192,000     500,000                
Other Accrued Liabilities, Noncurrent               793,000                
Asset Retirement Obligation, Accretion Expense 39,000 34,500 114,000 100,500                        
Operating Leases, Rent Expense, Sublease Rentals     100,000                 100,000        
Impairment of Long-Lived Assets to be Disposed of     $ 400,000     $ 0 $ 400,000