Quarterly report pursuant to Section 13 or 15(d)

Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail)

v3.10.0.1
Fair Value Measurements - Changes in Fair Value of Financial Instruments (Detail)
$ in Thousands
9 Months Ended
Sep. 30, 2018
USD ($)
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance $ 21,833
Payment of convertible note (4,076)
Reclassification of warrant liability from debt to equity (13,615)
Change in fair value of investments (1,390)
Change in fair value of convertible notes (26)
Change in fair value of derivative liabilities 7,931
Balance 10,657
Helocyte Convertible Note At Fair Value [Member]  
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance 4,700
Payment of convertible note (4,076)
Reclassification of warrant liability from debt to equity 0
Change in fair value of investments 0
Change in fair value of convertible notes (291)
Change in fair value of derivative liabilities 0
Balance 333
Warrants Issued Issuable [Member]  
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance 5,597
Payment of convertible note 0
Reclassification of warrant liability from debt to equity (13,615)
Change in fair value of investments 0
Change in fair value of convertible notes 0
Change in fair value of derivative liabilities 8,018
Balance 0
Caelum Convertible Notes, at fair value [Member]  
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance 10,059
Payment of convertible note 0
Reclassification of warrant liability from debt to equity 0
Change in fair value of investments 0
Change in fair value of convertible notes 265
Change in fair value of derivative liabilities 0
Balance 10,324
Warrant liabilities [Member]  
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance 87
Payment of convertible note 0
Reclassification of warrant liability from debt to equity 0
Change in fair value of investments 0
Change in fair value of convertible notes 0
Change in fair value of derivative liabilities (87)
Balance 0
Investment In Origo [Member]  
Fair Value, Assets Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items]  
Balance 1,390
Payment of convertible note 0
Reclassification of warrant liability from debt to equity 0
Change in fair value of investments (1,390)
Change in fair value of convertible notes 0
Change in fair value of derivative liabilities 0
Balance $ 0