Accrued Expenses and Other Long-Term Liabilities - Additional Information (Detail) (USD $)
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3 Months Ended | 6 Months Ended | 3 Months Ended | 6 Months Ended | 6 Months Ended | 3 Months Ended | 6 Months Ended | 3 Months Ended | 6 Months Ended | ||||||
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Jun. 30, 2014
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Jun. 30, 2013
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Jun. 30, 2014
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Jun. 30, 2013
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Dec. 31, 2013
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Mar. 31, 2014
Manufacturing Facility [Member]
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Jun. 30, 2014
Manufacturing Facility [Member]
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Jun. 30, 2014
Ovamed Manufacturing Rights [Member]
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Dec. 31, 2012
Ovamed Manufacturing Rights [Member]
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Jun. 30, 2014
Woburn MA facility [Member]
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Jun. 30, 2014
New York NY Office Space [Member]
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Jun. 30, 2014
Lease Agreements [Member]
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Jun. 30, 2014
Lease Agreements [Member]
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Jun. 30, 2014
Chief Medical Officer [Member]
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Jun. 30, 2014
Chief Medical Officer [Member]
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Schedule Accrued Expenses And Other Long-Term Liabilities [Line Items] | |||||||||||||||
Other Research and Development Expense | $ 800,000 | ||||||||||||||
Lease Expiration Date | Feb. 28, 2018 | Feb. 28, 2018 | May 31, 2016 | ||||||||||||
Severance Costs | 400,000 | ||||||||||||||
Payments for Postemployment Benefits | 400,000 | 1,400,000 | |||||||||||||
Operating Leases, Rent Expense | 700,000 | 48,000 | |||||||||||||
Impairment of Long-Lived Assets Held-for-use | 300,000 | ||||||||||||||
Other Liabilities | 1,500,000 | ||||||||||||||
Other Accrued Liabilities Current | 161,000 | 161,000 | 192,000 | 500,000 | |||||||||||
Other Accrued Liabilities, Noncurrent | 754,000 | ||||||||||||||
Asset Retirement Obligation, Accretion Expense | 38,000 | 33,500 | 75,000 | 66,000 | |||||||||||
Operating Leases, Rent Expense, Sublease Rentals | 100,000 | 100,000 | |||||||||||||
Impairment of Long-Lived Assets to be Disposed of | $ 400,000 | $ 0 | $ 373,000 |