Annual report pursuant to Section 13 and 15(d)

Warrants to Purchase Common Stock - Additional Information (Detail)

v2.4.0.8
Warrants to Purchase Common Stock - Additional Information (Detail) (USD $)
1 Months Ended 12 Months Ended 90 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 12 Months Ended 1 Months Ended 0 Months Ended 12 Months Ended 12 Months Ended
Aug. 31, 2012
Jun. 30, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2013
Aug. 16, 2012
Dec. 31, 2012
Non Employee Warrants [Member]
Aug. 31, 2012
Non Employee Warrants [Member]
Apr. 30, 2012
Non Employee Warrants [Member]
Dec. 31, 2011
Non Employee Warrants [Member]
Sep. 30, 2011
Non Employee Warrants [Member]
Mar. 31, 2011
Non Employee Warrants [Member]
Feb. 28, 2011
Non Employee Warrants [Member]
Nov. 30, 2010
Non Employee Warrants [Member]
Dec. 31, 2013
Non Employee Warrants [Member]
Dec. 18, 2012
Non Employee Warrants [Member]
Aug. 28, 2012
Non Employee Warrants [Member]
Aug. 16, 2012
Non Employee Warrants [Member]
Apr. 02, 2012
Non Employee Warrants [Member]
Nov. 22, 2010
Non Employee Warrants [Member]
Sep. 30, 2011
Non Employee Warrants [Member]
Maximum [Member]
Sep. 30, 2011
Non Employee Warrants [Member]
Minimum [Member]
Apr. 30, 2012
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2013
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2013
National Securities Corporation [Member]
Dec. 31, 2013
National Securities Corporation [Member]
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2013
Debt Placement Agent Warrants [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Series A [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Senior Convertible Notes 2008 [Member]
Series A [Member]
Apr. 26, 2010
Debt Placement Agent Warrants [Member]
Senior Convertible Notes 2009 [Member]
Series A [Member]
Dec. 31, 2007
Common Stock [Member]
Apr. 30, 2012
Common Stock [Member]
Warrants to Purchase Series C Shares [Member]
Nov. 15, 2011
Common Stock [Member]
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2013
Common Stock [Member]
Warrants to Purchase Series C Shares [Member]
Apr. 02, 2012
Common Stock [Member]
Warrants to Purchase Series C Shares [Member]
Dec. 31, 2013
Preferred Stock Placement Warrants [Member]
Dec. 31, 2013
Preferred Stock Placement Warrants [Member]
Series A [Member]
Dec. 31, 2013
Preferred Stock Placement Warrants [Member]
Series A [Member]
Maximum [Member]
Dec. 31, 2013
Preferred Stock Placement Warrants [Member]
Series A [Member]
Minimum [Member]
Dec. 31, 2009
PCP Warrants [Member]
Dec. 31, 2011
PCP Warrants [Member]
Series A [Member]
Dec. 31, 2009
PCP Warrants [Member]
Series A [Member]
Warrants To Purchase Common Stock [Line Items]                                                                                        
Period of Issued Warrants                           5 years                           7 years                                
Notes Principal Amount Percentage                                                       10.00%   10.00%                       40.00%   40.00%
Warrant exercise price             5.72       6.00 2.95 1.37 1.37     4.88 5.65 5.72 1.37 9.23           5.59 1.00     9.23 9.23             8.39     1.00 6.15 9.23
Exercise price percentage                                                           110.00%                           110.00%
Issued warrants to purchase common stock             20,000       5,000 75,000 60,000 50,000     35,000 73,009 25,000 25,000 41,716           461,263       48,510 41,716             258,421       40,787 27,175
Fair value of the warrant             $ 92,000       $ 19,100 $ 144,000 $ 98,000 $ 69,000     $ 103,000   $ 113,000   $ 38,000               $ 200,000   $ 100,000 $ 100,000           $ 600,000           $ 47,000
Volatility 104.51%             97.45% 110.30%   91.10%   95.40% 93.20% 93.70%             96.30% 90.80%                       92.40%         94.40% 92.00%      
Risk free rate 1.06%             0.28% 0.83%   0.40%   3.58% 2.65% 1.40%             0.90% 0.40%                       0.93%         3.30% 2.00%      
Estimated per share fair value                                         $ 1.96                           $ 8.00       $ 3.45          
Dividend yield 0.00%             0.00% 0.00%   0.00% 0.00% 0.00% 0.00%                                                            
Fair Value Assumptions, Expected Term 6 years             3 years 5 years       10 years 5 years 5 years                                                          
Warrants issued                                       20,970                                                
Warrant Fair Value                   $ 8.50                                                                    
Stock Issued During Period Shares warrants Exercised                               78,710                                       78,636                
Cashless Exercise Of Warrants                               153,415                                       328,510                
Investment Warrants, Exercise Price                               $ 5.00               $ 5.59                       $ 5.45                
Stock Issued During Period Shares New Issues   5,750,000 10,558,422 3,361                                         340               2,125,096                      
Proceeds From Issuance Of Common Stock   26,400,000 92,399,000 28,855,000 193,000 121,452,000                                                           1,000                
Class of Warrant or Right, Outstanding                                                                       711,895                
Fee paid to National Securities Corporation as consideration for its services as the placement agent                                                   10.00%                                    
Fair value of warrants reduction in carrying amount in share                                                   1,300,000                                    
Amount Charge Due To Mark To Market Valuation Of Warrants Exercisable For Common Stock                                                                     1,400,000                  
Final fair value of common stock                                                                     $ 2,700,000                  
Common Stock Shares Issued     39,652,950 24,400,754   39,652,950                                                             534              
Common Stock Shares Exercised                                                                   2,986                    
Fair market value of common stock on the date of exercise                                               $ 6.81