Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - Additional Information (Detail)

v3.3.1.900
Commitments and Contingencies - Additional Information (Detail)
 1 Months Ended 12 Months Ended
Oct. 03, 2014
USD ($)
Oct. 31, 2015
USD ($)
ft²
Jan. 31, 2015
USD ($)
Nov. 30, 2014
USD ($)
ft²
Apr. 30, 2013
USD ($)
ft²
Jul. 31, 2012
USD ($)
ft²
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Dec. 31, 2012
USD ($)
ft²
Operating Leased Assets [Line Items]                    
Land Subject to Ground Leases | ft²   6,100                
Operating Leases, Rent Expense $ 2,700,000 $ 214,000                
Operating Leases, Rent Expense, Net, Total             $ 354,000 $ 354,000 $ 284,000  
Lease Expiration Period   5 years                
Reorganization Value, Net Realizable Value of Asset Dispositions               100,000    
Stock Issued During Period, Value, Stock Options Exercised     $ 82,000       $ 216,000 596,000 970,000  
Lease Expiration Date             Jun. 30, 2016      
Loss Contingency, Loss in Period             $ 1,000,000      
Research and Development Expense [Member]                    
Operating Leased Assets [Line Items]                    
Disposal Group, Including Discontinued Operation, Operating Expense               700,000    
Woburn, MA facility [Member]                    
Operating Leased Assets [Line Items]                    
Disposal Group, Including Discontinued Operation, Operating Expense               700,000    
Operating Leases, Future Minimum Payments, Remainder of Fiscal Year               300,000    
Reorganization Value, Net Realizable Value of Asset Dispositions               400,000    
New York, NY office space [Member]                    
Operating Leased Assets [Line Items]                    
Lease Expiration Period 15 years                  
Operating Leases, Income Statement, Sublease Revenue               100,000    
Opus Point Partners Management, LLC [Member]                    
Operating Leased Assets [Line Items]                    
Operating Leases, Rent Expense $ 500,000                  
Contracted Build Out Costs Associated With Lease             5,100,000      
Percentage of Rentable Area 20.00%                  
Prepaid Rent               $ 199,000    
TG Therapeutics, Inc [Member]                    
Operating Leased Assets [Line Items]                    
Operating Leases, Rent Expense $ 1,100,000                  
Contracted Build Out Costs Associated With Lease             $ 5,100,000      
Percentage of Rentable Area 40.00%                  
Journey Medical Corporation [Member]                    
Operating Leased Assets [Line Items]                    
Land Subject to Ground Leases | ft²       2,295            
Operating Leases, Rent Expense       $ 39,000            
Lease Agreements [Member]                    
Operating Leased Assets [Line Items]                    
Land Subject to Ground Leases | ft²         1,500 3,200       8,700
Operating Leases, Rent Expense         $ 122,000 $ 94,000       $ 118,000
Operating Leases, Rent Expense, Net, Total                   $ 596,000
Contracted Build Out Costs Associated With Lease                 $ 373,000  
Lease Termination Period     three years