Quarterly report pursuant to Section 13 or 15(d)

Debt and Interest- Additional Information (Detail)

v3.5.0.2
Debt and Interest- Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2016
Jun. 30, 2016
Feb. 29, 2016
Feb. 13, 2014
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Jun. 30, 2016
Sep. 30, 2015
Sep. 09, 2016
Jul. 31, 2016
Jul. 05, 2016
Dec. 31, 2015
Mar. 31, 2015
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 39.49%       39.49%   39.49%     9.00%        
Fees related to the loan agreement             $ 491,000   $ 0          
Notes Payable $ 14,900,000       $ 14,900,000   14,900,000              
Repayments of Debt     $ 2,800,000                      
Debt Instrument, Unamortized Discount 2,764,000       2,764,000   2,764,000           $ 835,000  
Class of Warrant or Right, Discount On warrant $ 1.9       $ 1.9   1.9              
Helocyte Inc [Member]                            
Debt [Line Items]                            
Class of Warrant or Right, Value of Securities Called by Warrants or Rights             $ 301,800              
Placement Fee,Percentage 0.00%       0.00%   0.00%              
Helocyte Inc [Member] | Conversion One [Member]                            
Debt [Line Items]                            
Class of Warrant or Right, Value of Securities Called by Warrants or Rights             $ 100,000              
Helocyte Inc [Member] | Conversion Two [Member]                            
Debt [Line Items]                            
Class of Warrant or Right, Value of Securities Called by Warrants or Rights             $ 201,800              
Letter of Credit [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 2.00%       2.00%   2.00%              
Letters of Credit Outstanding, Amount $ 1.5       $ 1.5   $ 1.5              
Israel Discount Bank Of New York [Member]                            
Debt [Line Items]                            
Debt Instrument, Face Amount       $ 15,000,000                    
Notes Payable $ 14,900,000       $ 14,900,000   $ 14,900,000              
IDB Promissory Note Payable [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 2.25%       2.25%   2.25%              
Debt Instrument, Face Amount       15,000,000                    
IDB Promissory Note Payable [Member] | Minimum [Member]                            
Debt [Line Items]                            
Debt Instrument, Unused Borrowing Capacity, Amount       100,000                    
Opus Credit Facility [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 12.00%       12.00%   12.00%              
Interest rate 12                          
Class of Warrant or Right, Value of Securities Called by Warrants or Rights $ 1,500,000                          
Class of Warrant or Right, Exercise Price Percentage of Warrants or Rights         3.00%                  
Warrants and Rights Outstanding $ 5.0       $ 5.0   $ 5.0              
NSC Note [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 8.00%       8.00%   8.00%              
Debt Instrument, Fee Amount                         $ 900,000  
Long-term Debt, Gross                     $ 3,600,000 $ 3,600,000    
Notes Payable                           $ 10,000,000
Debt Instrument, Term             10 years              
Debt Instrument, Interest Rate, Effective Percentage                         12.40%  
Contingently Issuable Warrants Percentage 25.00%       25.00%   25.00%       25.00%      
NSC Note [Member] | Issuable Warrant [Member]                            
Debt [Line Items]                            
Debt Instrument, Unamortized Discount $ 634,000       $ 634,000   $ 634,000              
NSC Note [Member] | Warrant [Member]                            
Debt [Line Items]                            
Debt Instrument, Unamortized Discount (Premium), Net, Total $ 114,000       114,000   114,000              
Long-term Debt, Fair Value     174,000                      
Hercules Note Payble [Member]                            
Debt [Line Items]                            
Fees related to the loan agreement         $ 242,000 $ 0 $ 491,000   $ 0          
Debt Instrument, Periodic Payment, Interest       100,000                    
Debt Instrument, Periodic Payment       $ 14,000,000                    
Helocyte Convertible Note [Member]                            
Debt [Line Items]                            
Debt Instrument, Term             18 months              
Proceeds from Issuance or Sale of Equity             $ 10,000,000              
Legal Fees               $ 25,000,000            
Class of Warrant or Right, Exercise Price Percentage of Warrants or Rights             110.00%              
Helocyte Convertible Note [Member] | Conversion One [Member]                            
Debt [Line Items]                            
Debt Instrument, Convertible, Terms of Conversion Feature   the lowest price per share at which equity securities of Helocyte are sold in such sale less a 33% discount and (b) a per share price based on a pre-offering valuation of $50.0 million divided by the number of common shares outstanding on a fully-diluted basis.                        
Helocyte Convertible Note [Member] | Conversion Two [Member]                            
Debt [Line Items]                            
Debt Instrument, Convertible, Terms of Conversion Feature   a discount to the price per share being paid in the Sale of Helocyte equal to 33% or (b) a conversion price per share based on a pre-sale valuation of $50.0 million divided by the fully-diluted common stock of Helocyte immediately prior to the Sale of Helocyte (excluding the notes).                        
Helocyte Convertible Note [Member] | Minimum [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 5.00%       5.00%   5.00%              
Helocyte Convertible Note [Member] | Maximum [Member]                            
Debt [Line Items]                            
Debt Instrument, Interest Rate, Stated Percentage 8.00%       8.00%   8.00%              
Debt Instrument, Face Amount $ 5,000,000       $ 5,000,000   $ 5,000,000              
NSC [Member]                            
Debt [Line Items]                            
Debt Instrument, Term             10 years              
Checkpoint [Member]                            
Debt [Line Items]                            
Debt Instrument, Unamortized Discount (Premium), Net, Total     $ 324,000                      
Checkpoint [Member] | NSC Note [Member]                            
Debt [Line Items]                            
Fees related to the loan agreement             $ 2,800,000              
Avenue [Member]                            
Debt [Line Items]                            
Debt Instrument, Unamortized Discount (Premium), Net, Total $ 370,000       $ 370,000   370,000              
Avenue [Member] | NSC Note [Member]                            
Debt [Line Items]                            
Fees related to the loan agreement             $ 3,600,000