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Debt and Interest - Additional Information (Detail) (USD $)
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3 Months Ended | 9 Months Ended | 87 Months Ended | 3 Months Ended | 9 Months Ended | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended | |||
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Sep. 30, 2013
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Sep. 30, 2012
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Sep. 30, 2013
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Sep. 30, 2012
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Sep. 30, 2013
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Dec. 31, 2012
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Sep. 30, 2013
Hercules Note [Member]
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Sep. 30, 2013
Hercules Note [Member]
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Oct. 31, 2013
Hercules Note [Member]
Subsequent Event [Member]
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Sep. 30, 2013
Ovamed Manufacturing Rights [Member]
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Sep. 30, 2013
Ovamed Manufacturing Rights [Member]
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Dec. 31, 2012
Ovamed Manufacturing Rights [Member]
Installment
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| Debt Instrument [Line Items] | ||||||||||||
| Accretion of obligation | $ 493,000 | $ 183,000 | $ 1,454,000 | $ 220,000 | $ 5,407,000 | $ 493,000 | $ 1,453,000 | $ 34,500 | $ 100,500 | |||
| Term loan with Hercules Technology Growth Capital | 15,000,000 | 15,000,000 | ||||||||||
| Cash interest paid | 355,000 | 1,052,000 | ||||||||||
| Interest expenses accretion of debt discounts | 99,000 | 286,000 | ||||||||||
| Current portion of note payable | 6,062,000 | 6,062,000 | 6,062,000 | 1,799,000 | 6,100,000 | 6,100,000 | ||||||
| Non current portion of notes payable | 8,408,000 | 8,408,000 | 8,408,000 | 12,386,000 | 8,900,000 | 8,900,000 | ||||||
| Debt discount recorded | 530,000 | 530,000 | ||||||||||
| First principal payment made | 446,000 | |||||||||||
| Payment to acquire manufacturing rights | 1,500,000 | |||||||||||
| Number of manufacturing rights installments | 3 | |||||||||||
| Installment for manufacturing rights | 500,000 | |||||||||||
| Acquired intangible assets payment initiation date | 2014-12 | |||||||||||
| Acquired intangible assets payment expiration date | 2016-12 | |||||||||||
| Net present value of long term liabilities | 1,000,000 | |||||||||||
| Interest rate on net present value | 12.33% | |||||||||||
| Carrying amount obligation | $ 1,500,000 | |||||||||||