Quarterly report pursuant to Section 13 or 15(d)

TSO (Details Textual)

v2.4.0.6
TSO (Details Textual)
1 Months Ended 3 Months Ended 81 Months Ended 1 Months Ended 3 Months Ended
Feb. 22, 2013
Mar. 31, 2013
USD ($)
Mar. 31, 2012
USD ($)
Mar. 31, 2013
USD ($)
Feb. 22, 2013
Research and Development Arrangement [Member]
USD ($)
Feb. 22, 2013
Research and Development Arrangement [Member]
EUR (€)
Mar. 31, 2013
Research and Development Arrangement [Member]
USD ($)
Feb. 22, 2013
Joint Ownership and Exclusive License Agreement FU Berlin [Member]
USD ($)
Feb. 22, 2013
Joint Ownership and Exclusive License Agreement FU Berlin [Member]
EUR (€)
Feb. 22, 2013
Joint Ownership and Exclusive License Agreement FU Berlin [Member]
Maximum [Member]
Feb. 22, 2013
Joint Ownership and Exclusive License Agreement FU Berlin [Member]
Minimum [Member]
Feb. 22, 2013
License and Sublicense Agreement with Ovamed GmbH [Member]
USD ($)
Feb. 22, 2013
License and Sublicense Agreement with Ovamed GmbH [Member]
EUR (€)
Feb. 22, 2013
License and Sublicense Agreement with Ovamed GmbH [Member]
Maximum [Member]
Feb. 22, 2013
License and Sublicense Agreement with Ovamed GmbH [Member]
Minimum [Member]
TSO (Textual) [Abstract]                              
Expected project duration under Research Agreement         4 years 4 years                  
Research and development expense   $ 5,974,000 $ 4,581,000 $ 47,983,000 $ 843,000 € 648,000 $ 22,000                
Written notice period under Research Agreement Termination         3 months 3 months                  
Potential milestone payments based primarily on the achievement of clinical development and regulatory milestones               4,982,000 3,830,000            
Percentage of royalty on net sales of products range                   2.50% 1.00%     2.50% 1.00%
Maximum potential payment based on achievement of regulatory milestones,                       $ 1,333,000 € 1,025,000    
Right Interest in Joint Intellectual Property 10.00%                            
Notice period to cure termination due to breach 60 days                            
Period of notice for termination of Joint Ownership and exclusive license agreement 60 days                            
Period of Written notice for termination of Joint Ownership and exclusive license agreement 180 days