Annual report pursuant to Section 13 and 15(d)

Debt and Interest (Detail 1)

v3.3.1.900
Debt and Interest (Detail 1) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Debt [Line Items]      
Interest $ 1,500 $ 1,300 $ 1,900
Amortization of fees 700 4,000  
Interest expense related to the Hercules loan 1,484 1,338 1,923
IDB Note [Member]      
Debt [Line Items]      
Interest 314 292 0
Accretion of debt discount 5 4 0
Interest and Debt Expense, Total 319 296 0
NSC Debt [Member]      
Debt [Line Items]      
Interest 690 0 0
Accretion of debt discount 309 0 0
Amortization of fees 300    
Interest and Debt Expense, Total 999 0 0
Ovamed Manufacturing Agreement [Member]      
Debt [Line Items]      
Interest 166 154 136
Interest and Debt Expense, Total 166 154 136
Hercules Debt [Member]      
Debt [Line Items]      
Interest [1] 0 845 1,767
Accretion of debt discount 0 400 400
Amortization of fees 0 43 20
Interest and Debt Expense, Total $ 0 $ 888 $ 1,787
[1] Interest expense related to the Company’s loan with Hercules was $0.8 million and 1.7 million, including $0.4 million and $0.3 million related to accretion of the debt discount for the years ended December 31, 2014 and 2013 respectively.