Annual report pursuant to Section 13 and 15(d)

Organization and Description of Business (Details Textual)

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Organization and Description of Business (Details Textual) (USD $)
 0 Months Ended 1 Months Ended 12 Months Ended 78 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended 78 Months Ended 0 Months Ended 12 Months Ended 78 Months Ended 0 Months Ended 12 Months Ended
Aug. 28, 2012
Jun. 27, 2012
Jun. 30, 2012
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Dec. 31, 2012
Market Issuance Sales Agreement [Member]
Nov. 15, 2011
Series A Convertible Preferred Stock [Member]
Dec. 31, 2010
Series A Convertible Preferred Stock [Member]
Dec. 31, 2012
Series A Convertible Preferred Stock [Member]
Nov. 15, 2011
Series B Convertible Preferred Stock [Member]
Nov. 15, 2011
Series C Convertible Preferred Stock [Member]
Dec. 31, 2011
Series C Convertible Preferred Stock [Member]
Dec. 31, 2012
Series C Convertible Preferred Stock [Member]
Jun. 27, 2012
Common Stock [Member]
Dec. 31, 2007
Common Stock [Member]
Organization and Description of Business (Textual) [Abstract]                                
Convertible Preferred Stock issued, Shares                 4,357,885       0 0    
Convertible Preferred Stock issued, amount                 $ 21,681,000 $ 21,681,000     $ 25,784,000 $ 25,784,000    
Convertible Preferred stock number of preferred stock converted into common stock               4,357,885     2,525,677 4,612,624        
Public offering of Common Stock, shares     5,750,000 3,361     1,426,250               5,750,000 2,125,096
Net proceeds from public offering of Common Stock   26,400,000   28,855,000 193,000 29,053,000 10,500,000                  
Organization and Description of Business (Additional Textual) [Abstract]                                
Accumulated deficit       (84,184,000) (56,574,000) (84,184,000)                    
Net proceeds from issuance of Term loan 14,700,000                              
Amount of term loan 15,000,000                              
Aggregate offering price of common stock       $ 30,000,000                        
Date of inception       Jun. 28, 2006