United States securities and exchange commission logo May 22, 2020 Lindsay A. Rosenwald, M.D. Executive Chairman, Chief Executive Officer and President Fortress Biotech, Inc. 2 Gansevoort Street, 9th Floor New York, New York 10014 Re: Fortress Biotech, Inc. Registration Statement on Form S-3 Filed May 18, 2020 File No. 333-238327 Dear Dr. Rosenwald: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tim Buchmiller at (202) 551-3635 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Mark McElreath, Esq.